{"id":2884,"date":"2026-01-29T22:38:05","date_gmt":"2026-01-29T14:38:05","guid":{"rendered":"http:\/\/www.majunpeng.com\/?p=2884"},"modified":"2026-02-01T23:30:24","modified_gmt":"2026-02-01T15:30:24","slug":"%e5%9f%ba%e4%ba%8e%e5%b7%b2%e5%8f%91%e8%a1%a8%e7%9a%84%e5%9f%ba%e5%9b%a0%e7%bb%84%e6%b3%a8%e9%87%8a%e7%bb%93%e6%9e%9c%e5%af%b9helixer%e8%bf%9b%e8%a1%8c%e5%be%ae%e8%b0%83","status":"publish","type":"post","link":"http:\/\/www.majunpeng.com\/index.php\/2026\/01\/29\/%e5%9f%ba%e4%ba%8e%e5%b7%b2%e5%8f%91%e8%a1%a8%e7%9a%84%e5%9f%ba%e5%9b%a0%e7%bb%84%e6%b3%a8%e9%87%8a%e7%bb%93%e6%9e%9c%e5%af%b9helixer%e8%bf%9b%e8%a1%8c%e5%be%ae%e8%b0%83\/","title":{"rendered":"\u57fa\u4e8e\u5df2\u53d1\u8868\u7684\u57fa\u56e0\u7ec4\u6ce8\u91ca\u7ed3\u679c\u5bf9Helixer\u8fdb\u884c\u5fae\u8c03"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2884\" class=\"elementor elementor-2884\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3a1b44f e-flex e-con-boxed e-con e-parent\" data-id=\"3a1b44f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-20e1040 e-con-full e-flex e-con e-child\" data-id=\"20e1040\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c9715f3 elementor-widget elementor-widget-heading\" data-id=\"c9715f3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u524d\u8a00<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31ee79f elementor-widget elementor-widget-text-editor\" data-id=\"31ee79f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"85\" data-end=\"228\">\u5728\u4e0a\u4e00\u7bc7\u6587\u7ae0\u4e2d\uff0c\u6211\u4eec\u7cfb\u7edf\u4ecb\u7ecd\u4e86 <strong data-start=\"101\" data-end=\"111\">ANNEVO<\/strong> \u4e0e <strong data-start=\"114\" data-end=\"125\">Helixer<\/strong> \u4e24\u6b3e\u57fa\u4e8e\u6df1\u5ea6\u5b66\u4e60\u7684\u4ece\u5934\u57fa\u56e0\u9884\u6d4b\u8f6f\u4ef6\u7684\u73af\u5883\u914d\u7f6e\u3001\u6a21\u578b\u8c03\u7528\u53ca\u5b9e\u9645\u4f7f\u7528\u6d41\u7a0b\u3002\u6574\u4f53\u800c\u8a00\uff0c\u8fd9\u7c7b\u65b9\u6cd5\u5728\u590d\u6742\u57fa\u56e0\u7ed3\u6784\u8bc6\u522b\u3001\u5f31\u8bc1\u636e\u533a\u57df\u9884\u6d4b\u4ee5\u53ca\u5927\u89c4\u6a21\u57fa\u56e0\u7ec4\u6ce8\u91ca\u4e2d\u5c55\u73b0\u51fa\u4e86\u663e\u8457\u4f18\u52bf\uff0c\u5df2\u9010\u6e10\u6210\u4e3a\u57fa\u56e0\u7ec4\u6ce8\u91ca\u6d41\u7a0b\u4e2d\u7684\u91cd\u8981\u7ec4\u6210\u90e8\u5206\u3002<\/p><p data-start=\"230\" data-end=\"466\">\u7136\u800c\uff0c\u5728\u5b9e\u9645\u5e94\u7528\u4e2d\u4e5f\u53ef\u4ee5\u660e\u663e\u611f\u53d7\u5230\uff0c\u8fd9\u4e24\u6b3e\u8f6f\u4ef6\u5b58\u5728\u4e00\u4e2a\u5171\u540c\u7684\u74f6\u9888\uff1a<strong data-start=\"263\" data-end=\"288\">\u5b98\u65b9\u63d0\u4f9b\u7684\u9884\u8bad\u7ec3\u6a21\u578b\u5728\u5206\u7c7b\u5c3a\u5ea6\u4e0a\u8fc7\u4e8e\u7c97\u7c92\u5ea6<\/strong>\u3002\u4ee5 Helixer \u4e3a\u4f8b\uff0c\u76ee\u524d\u6240\u6709\u9646\u751f\u690d\u7269\u5747\u7edf\u4e00\u4f7f\u7528\u540c\u4e00\u4e2a <em data-start=\"319\" data-end=\"331\">land_plant<\/em> 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data-end=\"544\">\u57fa\u4e8e\u7279\u5b9a\u7c7b\u7fa4\u7684\u9ad8\u8d28\u91cf\u57fa\u56e0\u7ec4\u4e0e\u6ce8\u91ca\u7ed3\u679c\uff0c\u5bf9\u73b0\u6709\u6a21\u578b\u8fdb\u884c\u9488\u5bf9\u6027\u7684\u5fae\u8c03\uff08fine-tuning\uff09\uff0c\u6784\u5efa\u201c\u7c7b\u7fa4\u611f\u77e5\u201d\u7684\u6ce8\u91ca\u6a21\u578b\uff0c\u5177\u6709\u91cd\u8981\u7684\u73b0\u5b9e\u610f\u4e49<\/strong>\u3002\u8fd9\u4e0d\u4ec5\u6709\u52a9\u4e8e\u63d0\u5347\u76ee\u6807\u7c7b\u7fa4\u4e2d\u65b0\u57fa\u56e0\u7ec4\u7684\u6ce8\u91ca\u51c6\u786e\u6027\u548c\u4e00\u81f4\u6027\uff0c\u4e5f\u4e3a\u5728\u66f4\u5927\u7cfb\u7edf\u53d1\u80b2\u5c3a\u5ea6\u4e0a\u6784\u5efa\u5206\u5c42\u3001\u53ef\u8fc1\u79fb\u7684\u6ce8\u91ca\u6a21\u578b\u63d0\u4f9b\u4e86\u53ef\u884c\u8def\u5f84\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2181640 elementor-widget elementor-widget-heading\" data-id=\"2181640\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u6784\u5efa\u8bad\u7ec3\u6570\u636e\u96c6<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1993ada elementor-widget elementor-widget-text-editor\" data-id=\"1993ada\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u51c6\u5907\u4e00\u4e2a\u5206\u7c7b\u5355\u5143\u4e0b\u6240\u6709\u5df2\u53d1\u8868\u57fa\u56e0\u7ec4\u7684\u6ce8\u91ca\u7ed3\u679c\uff0c\u8fd9\u4e9b\u57fa\u56e0\u7ec4\u6700\u597d\u662f\u9ad8\u8d28\u91cf\u7684\u67d3\u8272\u4f53\u6c34\u5e73\u4ee5\u4e0a\u7684\uff0c\u5e76\u4e14\u6ce8\u91ca\u7684\u65f6\u5019\u6574\u5408\u591a\u65b9\u8bc1\u636e\u5f97\u5230\u7684\u9ad8\u8d28\u91cf\u6ce8\u91ca\u3002\u6700\u540e\u901a\u8fc7GeenuFF\u5bf9\u6ce8\u91ca\u7ed3\u679c\u8fdb\u884c\u8fc7\u6ee4\uff0c\u5220\u9664\u5b58\u5728\u660e\u663e\u9519\u8bef\u7684\u6ce8\u91ca\u5e76\u50a8\u5b58\u5728sqlite\u6570\u636e\u5e93\u4e2d\u3002GeenuFF\u4e3b\u8981\u8fc7\u6ee4\u7684\u9519\u8bef\u6709\u8d77\u59cb\u5bc6\u7801\u5b50\u7f3a\u5931\u6216\u4f4d\u7f6e\u4e0d\u5bf9\u3001\u7ec8\u6b62\u5bc6\u7801\u5b50\u7f3a\u5931\u6216\u63d0\u524d\u51fa\u73b0\u3001 5&#8242; \u7aef\u76f8\u4f4d\u9519\u8bef\u30013&#8242; \u7aef\u76f8\u4f4d\u4e0d\u5339\u914d\u3001\u5916\u663e\u5b50\u91cd\u53e0\u548c\u5185\u542b\u5b50\u592a\u77ed \u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-86cb314 elementor-widget elementor-widget-heading\" data-id=\"86cb314\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u4e0b\u8f7dGeenuFF<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2ad6c09 elementor-widget elementor-widget-code-highlight\" data-id=\"2ad6c09\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"code-highlight.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"prismjs-okaidia copy-to-clipboard \">\n\t\t\t<pre data-line=\"\" class=\"highlight-height language-bash line-numbers\">\n\t\t\t\t<code readonly=\"true\" class=\"language-bash\">\n\t\t\t\t\t<xmp>git clone https:\/\/github.com\/weberlab-hhu\/GeenuFF.git\r\ncd GeenuFF\r\npip install -r requirements.txt\r\npip install .<\/xmp>\n\t\t\t\t<\/code>\n\t\t\t<\/pre>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bce74b3 elementor-widget elementor-widget-heading\" data-id=\"bce74b3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">GeenuFF\u5bf9\u6ce8\u91ca\u7ed3\u679c\u8fdb\u884c\u8fc7\u6ee4\uff0c\u5e76\u8f6c\u6362\u4e3asqlite<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-602dd0b elementor-widget elementor-widget-code-highlight\" data-id=\"602dd0b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"code-highlight.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"prismjs-okaidia copy-to-clipboard \">\n\t\t\t<pre data-line=\"\" class=\"highlight-height language-bash line-numbers\">\n\t\t\t\t<code readonly=\"true\" class=\"language-bash\">\n\t\t\t\t\t<xmp>python3 import2geenuff.py --gff3 Prunus_mongolica_Chr.gff \\\n--fasta Prunus_mongolica_Chr.genome_trimmed.fasta \\\n--db-path Prunus_mongolica.sqlite3 \\\n--log-file Prunus_mongolica.log \\\n--species Prunus_mongolica\n\n# --fasta \u57fa\u56e0\u7ec4\u6587\u4ef6\n# --gff3 \u57fa\u56e0\u7ec4\u6ce8\u91ca\u6587\u4ef6\n# --db-path \u8f93\u51faqlite\u6587\u4ef6 \n# --log-file log\u6587\u4ef6 \n# --species \u7269\u79cd <\/xmp>\n\t\t\t\t<\/code>\n\t\t\t<\/pre>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4ea8598 elementor-widget elementor-widget-heading\" data-id=\"4ea8598\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">sqlite\u8f6c\u6362\u4e3aHelixer\u8bad\u7ec3\u6570\u636e\u8981\u6c42\u7684h5\u6587\u4ef6<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b7c72e6 elementor-widget elementor-widget-code-highlight\" data-id=\"b7c72e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"code-highlight.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"prismjs-okaidia copy-to-clipboard \">\n\t\t\t<pre data-line=\"\" class=\"highlight-height language-bash line-numbers\">\n\t\t\t\t<code readonly=\"true\" class=\"language-bash\">\n\t\t\t\t\t<xmp>apptainer run --nv ~\/helixer-docker_latest.sif geenuff2h5.py \\\n--input-db-path  Prunus_mongolica.sqlite3 \\\n--h5-output-path Prunus_mongolica.h5<\/xmp>\n\t\t\t\t<\/code>\n\t\t\t<\/pre>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8a9502d elementor-widget elementor-widget-text-editor\" data-id=\"8a9502d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u5c06\u6bcf\u4e2a\u7528\u4f5c\u8bad\u7ec3\u548c\u9a8c\u8bc1\u7684\u7269\u79cd\u7684\u57fa\u56e0\u7ec4\u5bf9\u5e94\u7684h5\u6587\u4ef6\u6574\u7406\u5230\u4e00\u4e2a\u6587\u4ef6\u5939\u4e2d\uff0c\u8bad\u7ec3\u6570\u636e\u96c6\u7684h5\u6587\u4ef6\u540d\u5e76\u4e14\u7b26\u5408training_data*\u683c\u5f0f\uff0c\u9a8c\u8bc1\u7684\u6570\u636e\u96c6h5\u6587\u4ef6\u540d\u5fc5\u987b\u7b26\u5408validation_data*\uff0c\u4e0d\u7136\u4f1a\u62a5\u9519\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-744a396 elementor-widget elementor-widget-heading\" data-id=\"744a396\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u8bad\u7ec3\u6a21\u578b<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c3b89d5 elementor-widget elementor-widget-code-highlight\" data-id=\"c3b89d5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"code-highlight.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"prismjs-okaidia copy-to-clipboard \">\n\t\t\t<pre data-line=\"\" class=\"highlight-height language-bash line-numbers\">\n\t\t\t\t<code readonly=\"true\" class=\"language-bash\">\n\t\t\t\t\t<xmp>apptainer run --nv ~\/helixer-docker_latest.sif HybridModel.py \\\n--data-dir train \\\n--save-model-path best_helixer_model.h5 \\\n--epochs 50  \\\n--predict-phase \\\n--load-model-path \/home\/majunpeng\/.local\/share\/Helixer\/models\/land_plant\/land_plant_v0.3_a_0080.h5\\\n--resume-training\n\n# --data-dir \u8bad\u7ec3\u548c\u9a8c\u8bc1\u6570\u636e\u96c6\u7684\u8def\u5f84 \n# --save-model-path \u8bad\u7ec3\u540e\u7684\u6a21\u578b \n# --epochs 50\n# --load-model-path \u52a0\u8f7d\u7684\u6a21\u578b <\/xmp>\n\t\t\t\t<\/code>\n\t\t\t<\/pre>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eb166d5 elementor-widget elementor-widget-text-editor\" data-id=\"eb166d5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>20260201\u8865\u5145\uff1a\u4e0d\u77e5\u9053\u914d\u7f6e\u4e86\u4ec0\u4e48\uff0c\u73b0\u5728\u8981\u52a0\u4e0a&#8211;env PYTHONNOUSERSITE=1\u624d\u80fd\u6210\u529f\u8fd0\u884c\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ac660be elementor-widget elementor-widget-text-editor\" data-id=\"ac660be\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u968f\u540e\u4f1a\u5bf9\u6a21\u578b\u8fdb\u884c\u8bad\u7ec3\uff0c\u5e76\u7edf\u8ba1\u8bad\u7ec3\u540e\u6a21\u578b\u7684\u4e00\u4e9b\u6307\u6807\uff0c\u8861\u91cf\u8bad\u7ec3\u6a21\u578b\u9884\u6d4b\u57fa\u56e0\u7684\u51c6\u786e\u5ea6\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b9a4f10 elementor-widget elementor-widget-image\" data-id=\"b9a4f10\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"773\" height=\"787\" src=\"http:\/\/www.majunpeng.com\/wp-content\/uploads\/2026\/01\/a1911ea5-8af3-4700-8309-4b345d5b3fb1.png\" class=\"attachment-large size-large wp-image-2893\" alt=\"\" srcset=\"http:\/\/www.majunpeng.com\/wp-content\/uploads\/2026\/01\/a1911ea5-8af3-4700-8309-4b345d5b3fb1.png 773w, http:\/\/www.majunpeng.com\/wp-content\/uploads\/2026\/01\/a1911ea5-8af3-4700-8309-4b345d5b3fb1-295x300.png 295w, http:\/\/www.majunpeng.com\/wp-content\/uploads\/2026\/01\/a1911ea5-8af3-4700-8309-4b345d5b3fb1-768x782.png 768w\" sizes=\"(max-width: 773px) 100vw, 773px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c4a1b35 elementor-widget elementor-widget-heading\" data-id=\"c4a1b35\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u8bad\u7ec3\u6a21\u578b\u7ed3\u679c\u89e3\u8bfb<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-80a7644 elementor-widget elementor-widget-text-editor\" data-id=\"80a7644\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u9996\u5148\u6765\u770b\u4e0b\u57fa\u56e0\u7ec4\u56db\u4e2a\u533a\u57df\u7684\u542b\u4e49\uff1a<\/p><p>ig\uff1a\u57fa\u56e0\u95f4\u9694\u533a<\/p><p>utr\uff1aUTR\u533a<\/p><p>exon\uff1a\u5916\u663e\u5b50<\/p><p>intron\uff1a\u5185\u542b\u5b50<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-42be593 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"42be593\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f42c9de elementor-widget elementor-widget-text-editor\" data-id=\"f42c9de\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Confusion Matrix\uff1a\u7edf\u8ba1\u6bcf\u4e2a\u78b1\u57fa\u7684\u5206\u7c7b\u7ed3\u679c\uff0c\u6bcf\u4e00\u4e2a\u78b1\u57fa\uff0c\u90fd\u88ab\u6a21\u578b\u9884\u6d4b\u6210 4 \u7c7b\u4e4b\u4e00\uff0c\u540c\u65f6\uff0c\u8be5\u78b1\u57fa\u5728\u53c2\u8003\u6ce8\u91ca\u4e2d\u4e5f\u5c5e\u4e8e\u8fd9 4 \u7c7b\u4e4b\u4e00\u3002\u56e0\u6b64\uff0c\u6df7\u6dc6\u77e9\u9635\u5c31\u662f<strong data-start=\"263\" data-end=\"284\">\u771f\u5b9e\u7c7b\u522b\uff08\u884c\uff09 \u00d7 \u9884\u6d4b\u7c7b\u522b\uff08\u5217\uff09<\/strong> \u7684\u78b1\u57fa\u6570\u91cf\u7edf\u8ba1\u3002<\/p><p>\u6bd4\u5982| exon_ref | 5014284 | 2002047 | 2001614 | 134915 |<\/p><p data-start=\"548\" data-end=\"551\">\u8868\u793a\u6709 <strong data-start=\"557\" data-end=\"582\">5,014,284 bp \u7684\u771f\u5b9e exon<\/strong>\u88ab\u9884\u6d4b\u6210 <strong data-start=\"592\" data-end=\"598\">IG\uff1b<\/strong>\u6709 <strong data-start=\"603\" data-end=\"619\">2,001,614 bp<\/strong>\u88ab\u9884\u6d4b\u6210 <strong data-start=\"629\" data-end=\"641\">exon\uff08\u6b63\u786e\uff09<\/strong><\/p><p data-start=\"548\" data-end=\"551\">Normalized Confusion Matrix\uff1a\u5bf9Confusion Matrix\u6309\u884c\u5f52\u4e00\u5316\uff08row-normalized\uff09\u3002<\/p><p data-start=\"548\" data-end=\"551\">F1_summary\uff1a\u7edf\u8ba1\u4e86\u6bcf\u4e2a\u533a\u57df\u7684\u53ec\u56de\u7387\u3001\u51c6\u786e\u7387\u548cF1-score\u3002\u4e0b\u9762\u4e09\u4e2a\u6307\u6807\u4ec0\u4e48\u610f\u601d\u6ca1\u641e\u61c2\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0ba03ea elementor-widget elementor-widget-image\" data-id=\"0ba03ea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"947\" height=\"695\" src=\"http:\/\/www.majunpeng.com\/wp-content\/uploads\/2026\/01\/f1acfc17-4cb1-41df-8005-fc182d1d2dbf.png\" class=\"attachment-large size-large wp-image-2894\" alt=\"\" srcset=\"http:\/\/www.majunpeng.com\/wp-content\/uploads\/2026\/01\/f1acfc17-4cb1-41df-8005-fc182d1d2dbf.png 947w, http:\/\/www.majunpeng.com\/wp-content\/uploads\/2026\/01\/f1acfc17-4cb1-41df-8005-fc182d1d2dbf-300x220.png 300w, http:\/\/www.majunpeng.com\/wp-content\/uploads\/2026\/01\/f1acfc17-4cb1-41df-8005-fc182d1d2dbf-768x564.png 768w\" sizes=\"(max-width: 947px) 100vw, 947px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-45ca558 elementor-widget elementor-widget-text-editor\" data-id=\"45ca558\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u548c\u4e0a\u9762\u7edf\u8ba1\u7684\u6307\u6807\u7c7b\u4f3c\uff0c\u53ea\u4e0d\u8fc7\u5173\u6ce8\u7684\u662fphase\u3002phase \u63cf\u8ff0\u7684\u662f\uff1a\u67d0\u4e00\u4e2a\u78b1\u57fa\u5728 CDS \u5bc6\u7801\u5b50\uff08\u4e09\u8054\u4f53\uff09\u4e2d\u7684\u4f4d\u7f6e\u3002\u56e0\u6b64\u8fd9\u91cc\u7edf\u8ba1\u7684\u7684\u662fCDS\u5185\u90e8\u6bcf\u4e2a\u5bc6\u7801\u5b50\u7684\u4f4d\u7f6e\u9884\u6d4b\u7684\u51c6\u786e\u7387\uff0c\u5173\u6ce8\u7684\u662fCDS\u5185\u90e8\u6709\u6ca1\u6709\u51fa\u73b0\u79fb\u7801\u7b49\u9519\u8bef\u3002<\/p><table><thead><tr><th>phase<\/th><th>\u542b\u4e49<\/th><\/tr><\/thead><tbody><tr><td>phase 0<\/td><td>\u5bc6\u7801\u5b50\u7684\u7b2c 1 \u4e2a\u78b1\u57fa<\/td><\/tr><tr><td>phase 1<\/td><td>\u5bc6\u7801\u5b50\u7684\u7b2c 2 \u4e2a\u78b1\u57fa<\/td><\/tr><tr><td>phase 2<\/td><td>\u5bc6\u7801\u5b50\u7684\u7b2c 3 \u4e2a\u78b1\u57fa<\/td><\/tr><tr><td>no_phase<\/td><td>\u4e0d\u5728 CDS \u4e2d<\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d393cda elementor-widget elementor-widget-text-editor\" data-id=\"d393cda\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>\u7efc\u5408\u4e00\u53e5\u8bdd\u5c31\u662f\uff0c\u7b2c\u4e00\u4e2a\u8868\u7edf\u8ba1\u7684\u662f\uff0c\u57fa\u56e0\u533a\u57df\u9884\u6d4b\u7684\u51c6\u4e0d\u51c6\uff0c\u7b2c\u4e8c\u4e2a\u8868\u7edf\u8ba1\u7684\u662f\u57fa\u56e0\u5185\u90e8CDS\u9884\u6d4b\u7684\u5bf9\u4e0d\u5bf9\u3002<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-18830d5 elementor-widget elementor-widget-heading\" data-id=\"18830d5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u7ed3\u8bed<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d1b42da elementor-widget elementor-widget-text-editor\" data-id=\"d1b42da\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u7ecf\u8fc7\u6211\u81ea\u5df1\u6d4b\u8bd5\u4e0b\u6765\uff0c\u9488\u5bf9\u67d0\u4e00\u4e2a\u7c7b\u7fa4\u8fdb\u884c\u5355\u72ec\u7684\u6a21\u578b\u8bad\u7ec3\uff0c\u5f97\u5230\u4e00\u4e2a\u9488\u5bf9\u5355\u4e2a\u7c7b\u7fa4\u7684\u6ce8\u91ca\u6a21\u578b\u662f\u771f\u91cd\u8981\u7684\uff0c\u5bf9\u6ce8\u91ca\u7684\u7ed3\u679c\u6709\u826f\u597d\u7684\u6539\u5584\u3002\u540e\u7eed\u51c6\u5907\u9488\u5bf9\u8fd9\u4e2a\u65b9\u9762\u5355\u72ec\u53d1\u8868\u4e00\u7bc7\u6587\u7ae0\uff0c\u6b22\u8fce\u6709\u57fa\u56e0\u7ec4\u57fa\u7840\u548c\u673a\u5668\u5b66\u4e60\u57fa\u7840\u8001\u5e08\u548c\u540c\u5b66\u8054\u7cfb\u6211\uff0c\u4e00\u8d77\u5408\u505a\u7814\u7a76\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u524d\u8a00 \u5728\u4e0a\u4e00\u7bc7\u6587\u7ae0\u4e2d\uff0c\u6211\u4eec\u7cfb\u7edf\u4ecb\u7ecd\u4e86 ANNEVO \u4e0e Helixer \u4e24\u6b3e\u57fa\u4e8e\u6df1\u5ea6\u5b66\u4e60\u7684\u4ece\u5934\u57fa\u56e0\u9884\u6d4b\u8f6f\u4ef6\u7684\u73af &#8230; <a title=\"\u57fa\u4e8e\u5df2\u53d1\u8868\u7684\u57fa\u56e0\u7ec4\u6ce8\u91ca\u7ed3\u679c\u5bf9Helixer\u8fdb\u884c\u5fae\u8c03\" class=\"read-more\" href=\"http:\/\/www.majunpeng.com\/index.php\/2026\/01\/29\/%e5%9f%ba%e4%ba%8e%e5%b7%b2%e5%8f%91%e8%a1%a8%e7%9a%84%e5%9f%ba%e5%9b%a0%e7%bb%84%e6%b3%a8%e9%87%8a%e7%bb%93%e6%9e%9c%e5%af%b9helixer%e8%bf%9b%e8%a1%8c%e5%be%ae%e8%b0%83\/\" aria-label=\"\u9605\u8bfb \u57fa\u4e8e\u5df2\u53d1\u8868\u7684\u57fa\u56e0\u7ec4\u6ce8\u91ca\u7ed3\u679c\u5bf9Helixer\u8fdb\u884c\u5fae\u8c03\">\u9605\u8bfb\u66f4\u591a<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_crdt_document":"","footnotes":""},"categories":[6],"tags":[],"class_list":["post-2884","post","type-post","status-publish","format-standard","hentry","category-6"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u57fa\u4e8e\u5df2\u53d1\u8868\u7684\u57fa\u56e0\u7ec4\u6ce8\u91ca\u7ed3\u679c\u5bf9Helixer\u8fdb\u884c\u5fae\u8c03 - \u5c0f\u9a6c\u751f\u4fe1\u65e5\u8bb0<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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